Thrifty Gene and Obesity

Thrifty Gene and obesity
Thrifty Gene and obesity
Over the last 50 years, there has been a major epidemic of obesity and associated co-morbidities, the so-called ‘metabolic syndrome’, mostly in the western world but with an increasingly global dimension. Obesity is the result of chronic energy imbalance in a person who consistently takes in more calories from food and drink that are needed to power their body’s metabolic and physical functions. The development of such chronic diseases has a strong
genetic component, yet the timescale of their increase cannot reflect a population genetic change. Consequently,
the most accepted model is that obesity and its sequelae are a result of a gene-environment interaction, an ancient
genetic selection to deposit fat efficiently that is maladaptive in modern society.

Obesity Statistics : –

The rapidly rising population prevalence of obesity in recent decades has been attributed to an “obesogenic” environment, which offers ready access to high-calorie foods but limits opportunities for physical activity. The obesity epidemic can be considered a collective response to this environment.


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